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Cosa (chi) è WAVE regulatory complex - definizione
WAVE regulatory complex
The WAVE regulatory complex (WRC, SCAR complex) is a five-subunit protein complex in the Wiskott-Aldrich syndrome protein (WASP) family involved in the formation of the actin cytoskeleton through interaction with the Arp2/3 complex. The holocomplex comprises WAVE1 (also known as WASF1), CYFIP1, ABI2, Nap1 and HSPC300 in its canonical form, or orthologues of these.
Regulatory sequence
![transcription start site]] of the gene. The loop is stabilized by one architectural protein anchored to the enhancer and one anchored to the promoter and these proteins are joined to form a dimer (red zigzags). Specific regulatory [[transcription factor]]s bind to DNA sequence motifs on the enhancer. General transcription factors bind to the promoter. When a transcription factor is activated by a signal (here indicated as [[phosphorylation]] shown by a small red star on a transcription factor on the enhancer) the enhancer is activated and can now activate its target promoter. The active enhancer is transcribed on each strand of DNA in opposite directions by bound RNAP IIs. Mediator (a complex consisting of about 26 proteins in an interacting structure) communicates regulatory signals from the enhancer DNA-bound transcription factors to the promoter.](https://commons.wikimedia.org/wiki/Special:FilePath/Regulation of transcription in mammals.jpg?width=200 "transcription start site]] of the gene. The loop is stabilized by one architectural protein anchored to the enhancer and one anchored to the promoter and these proteins are joined to form a dimer (red zigzags). Specific regulatory [[transcription factor]]s bind to DNA sequence motifs on the enhancer. General transcription factors bind to the promoter. When a transcription factor is activated by a signal (here indicated as [[phosphorylation]] shown by a small red star on a transcription factor on the enhancer) the enhancer is activated and can now activate its target promoter. The active enhancer is transcribed on each strand of DNA in opposite directions by bound RNAP IIs. Mediator (a complex consisting of about 26 proteins in an interacting structure) communicates regulatory signals from the enhancer DNA-bound transcription factors to the promoter.")
TYPE OF NUCLEIC ACID THAT AFFECTS THE EXPRESSION OF ASSOCIATED GENES
Regulatory regions; Regulatory region; Regulatory elements; Regulatory element; Regulatory sequences, ribonucleic acid; Regulatory sequences; Negative regulatory element; A-box; Regulatory region or sequence
A regulatory sequence is a segment of a nucleic acid molecule which is capable of increasing or decreasing the expression of specific genes within an organism. Regulation of gene expression is an essential feature of all living organisms and viruses.
Regulatory agency
GOVERNMENT AGENCY RESPONSIBLE FOR EXERCISING AUTONOMOUS AUTHORITY OVER SOME AREA OF HUMAN ACTIVITY IN A REGULATORY OR SUPERVISORY CAPACITY
Independent regulatory commission; Regulatory Agency; Regulatory authority; Regulator (economics); Independent regulatory agency; Independent Regulatory Commission; National regulatory authority; Economic regulator; Independent agency; Independent agencies; Regulatory Authority; Independent body; National regulatory agency; Regulatory body; Statutory regulator; Regulatory agencies; Regulatory authorities
A regulatory agency (regulatory body, regulator) or independent agency (independent regulatory agency) is a government authority that is responsible for exercising autonomous dominion over some area of human activity in a licensing and regulating capacity.
